The best 10 day Argentina itinerary

This 10-day Argentina itinerary covers this country's must-see spots—Buenos Aires, the wine country in Mendoza, and the renown Iguazu Falls. I’ve planned it to make travel efficient, so you can fully enjoy each location. It’s designed with first-time visitors in mind, including practical tips on where to stay, how to get around, and what to do, all based on my personal experiences. 

Is 10 days enough for Argentina?

A 10-day itinerary offers a wonderful introduction to Argentina, but keep in mind this is a vast country with diverse regions, each worth exploring. With limited time, it’s best to prioritize one or two areas rather than attempting a whirlwind tour that leaves little time for actually experiencing anything. Argentina’s size—it's the 8th largest country—means most travel between cities requires flights; for instance, Buenos Aires to Iguazu Falls is over 1,300 kilometers.

On my trips to Argentina, I appreciated not cramming in too many stops; skipping an extra city allowed me to fully enjoy each destination. I designed this itinerary with this idea in mind.  

The best time for this itinerary is during its spring (October to December) or fall (March to May). During these months, the temperatures are mild, without dealing with the summer crowds or the chill of winter.  

Editor's tip: make sure to check out all our Argentina itineraries.

Day 1: Arrive in Buenos Aires

This journey begins the moment you land at Ezeiza International Airport (EZE), 20 miles from the city center. If you're looking for a reliable ride into town, Manuel Tienda León buses depart every 30 minutes from Terminal A, dropping you off at their terminal in Madero Center (721 Eduardo Madero Avenue).

Downloading the Cabify app beforehand will be helpful – it’s the ideal way to get from the city terminal to your hotel with minimal hassle.

For a more direct route, head to the official Remis Ezeiza counter in the arrivals hall for a private car transfer, which guarantees door-to-door service without any of the guesswork. Avoid the unofficial taxi drivers who approach you at arrivals – they may seem friendly, but overcharging tourists is a common issue here.

Where to stay in Buenos Aires

Here's a quick look at Buenos Aires' neighborhoods: for a better breakdown, see our full guide on where to stay in Buenos Aires.

• Palermo Soho shines as the ideal first-time neighborhood. It’s vibrant and trendy. Its colorful murals and open-air cafes set the scene for an ideal day-to-night atmosphere.
• Palermo Hollywood, on the other hand, is known for its nightlife, with an array of bars, breweries, and restaurants that draw a lively evening crowd.
• Recoleta: Recoleta embodies classic elegance. Known for its French-style architecture, this area is home to Buenos Aires's most luxurious hotels, historic mansions, and high-end shops.
• San Telmo: With its cobblestone streets, colonial buildings, and weekly Sunday fair, San Telmo offers an authentic, laid-back vibe. This area is a haven for antique lovers, artists, and musicians, packed with historic cafes, tango clubs, and intimate bars.
• For a more local experience, venture into Chacarita or Villa Crespo. These lesser-known neighborhoods reveal a more down-to-earth side of Buenos Aires, with a vibrant mix of local eateries, unpretentious bars, and authentic street life.

Day 2: Explore Buenos Aires

Buenos Aires is one of South America's largest cities, home to nearly 16 million people in its metropolitan area. Known for its European-style architecture, vibrant cultural scene, and status as the birthplace of tango, this port city has been a major South American hub since its founding in 1536.

Things to do in Buenos Aires

Here are some of my favorite things to do in Buenos Aires — though the list could truly go on for much longer.

Start your day at a classic café

I wholly recommend breakfast at Las Violetas, a beloved Buenos Aires institution. The grand, old-world charm here is undeniable, from the stained glass windows to the marble pillars. Their breakfast tray, laden with freshly baked medialunas, pastries, and coffee, is a perfect welcome to the city.

Explore the historic center

Head to Plaza de Mayo, the heart of Argentine history and politics. The iconic pink Casa Rosada stands tall, a place where legends like Eva Perón once addressed the nation. Walk north along pedestrian-only Florida Street, stopping by the ornate Galerías Pacífico, even if you’re just there for a peek.

Cultural circuit

The MALBA museum is a must for contemporary art lovers, featuring some of Latin America’s best collections. Afterward, wind down with a stroll through the Rose Garden in Palermo. If you’re seeking a serene escape, the Japanese Gardens are a short walk away.

Hora del Vermut

In Buenos Aires, vermouth hour is widely celebrated. Head to Bar El Federal in San Telmo, a time-honored spot for this classic combo of vermouth, soda, and a picada (a plate of meats and cheeses). Wrap up your day with a reservation at a closed-door restaurant.

Day 3: Day trip to Colonia del Sacramento

Colonia del Sacramento, Uruguay's oldest city, is a UNESCO World Heritage Site where cobblestone streets and colonial architecture transport you back to the 17th century and is worth taking a day trip to (or, potentially even expanding your trip a few days).

Strolling through Colonia, you’ll notice a mix of architectural styles, tree-lined streets, and open plazas that reflect the town’s layered history and timeless appeal. With its waterfront views, cozy cafes, and walkable historic district, Colonia offers a refreshing escape from the city.

How to visit Colonia del Sacramento

From Buenos Aires’ Puerto Madero terminal, you can reach Colonia in about 1 hour and 15 minutes on the fast ferry (Buquebus). Slower ferries take closer to 3 hours but are more budget-friendly. During peak season, tickets can sell out, so booking at least a day in advance is recommended.

Taking the 8:15 AM fast ferry and returning on the 4:30 PM trip allows for a full day to explore. Remember, Uruguay is one hour ahead of Buenos Aires, so set your watch accordingly.

Things to do in Colonia del Sacramento

It’s a good idea to exchange some money in Buenos Aires before leaving, as exchange rates at Colonia’s port aren’t as favorable. Also, have your passport handy for immigration checks at both ports.

Lighthouse and historic walls

The 19th-century lighthouse is one of Colonia’s standout spots, offering panoramic views over the historic quarter and the Río de la Plata. Climb the 118 steps for a bird’s-eye perspective of the old city walls and colonial architecture below. Mid-morning light is perfect here, especially if you’re hoping to capture some photos.

Museum Quarter

For a glimpse into Colonia’s layered history, take a walk through the museum quarter. Start at the former governor’s house, which houses an intriguing collection of colonial artifacts. Just a few minutes away, you’ll find the tile museum and indigenous museum – both covered by a combined ticket.

Barrio Histórico

Stroll down the Street of Sighs, a picturesque lane lined with preserved 17th-century Portuguese houses. Take a moment to explore the Portón de Campo (the city gate) and the restored city walls, where the atmosphere is quiet and perfect for taking your time. This area invites a slower pace.

When it’s time for a break, head to Plaza Mayor 25 de Mayo. This lively square, with its shaded outdoor seating and welcoming cafes, is a great place to relax and enjoy a leisurely lunch.

Day 4: Travel from Buenos Aires to Iguazú Falls

Travel time: 1 hour 45 minutes flight from Jorge Newbery Airport (AEP) to Puerto Iguazú International Airport (IGR). Add 2 hours more for potential traffic.

A quick flight takes you from the cityscape of Buenos Aires to the lush surroundings of the Iguazú Falls. Catch an early morning flight from Jorge Newbery Airport (AEP) to Puerto Iguazú International Airport (IGR) – it’s a great way to make the most of your day.

When I made this trip, the first flight of the day was ideal for getting started early. A taxi ride from Palermo to Jorge Newbery Airport takes around 15 minutes, and once you arrive in Iguazú, it’s another short 20-minute drive to reach the town of Puerto Iguazú.

Where to stay near the Iguazú Falls

Choosing your stay near the Iguazú Falls depends on the experience you’re looking for. Here’s a quick guide to the main options:

• Puerto Iguazú: This bustling tourist town has plenty of restaurants, hotels, and amenities, and it’s convenient for access to the falls and local attractions.
• Inside Iguazú National Park: The exclusive Gran Meliá hotel is the only lodging within the park, offering incredible waterfall views and early-morning access to the trails before crowds arrive. Staying here gives you a chance to experience the falls in a more intimate, peaceful setting.
• 600 Hectáreas: For a quieter, nature-immersed experience, this jungle district features luxury eco-lodges tucked away from the busier areas.

Day 5: Explore the Iguazú Falls

Iguazú Falls is a breathtaking natural wonder, where 275 waterfalls cascade over nearly two miles of lush rainforest. The Argentine side lets you get up close to these spectacular falls, thanks to a network of walkways and viewpoints that bring you right to the heart of the action.

How to visit Iguazú Falls

Arriving at sunrise is key to avoiding both the crowds and the midday heat. When I visited, I arrived right as the gates opened, and it was incredible to have the Devil’s Throat viewpoint almost to myself. Head straight to the train that takes you to Devil’s Throat station, then work your way back through the Upper and Lower circuits.

The park has three main circuits:

• Devil’s Throat: The most iconic section of the falls, where you’re right at the edge of roaring water. Allow about 2 hours to take it all in.
• Upper Circuit: Elevated walkways above the falls provide sweeping views from above. Plan about 2 hours for this route.
• Lower Circuit: For close-up views from below, this circuit takes you deeper into the rainforest and offers different perspectives on the falls. Reserve 3 hours for this walk.

Start with Devil’s Throat in the morning, when the light is ideal for photos. Once you’ve returned via the train, head to the Upper Circuit before the day gets too warm. Save the Lower Circuit for the afternoon; the sun’s angle at that time often creates rainbows in the mist.

Pack your own snacks and water, as the only dining options are near the park entrance. The early morning and late afternoon are the best times to spot wildlife, so keep an eye out while walking through the trails.

Wildlife encounters in the rainforest

The rainforest surrounding the falls is alive with wildlife. Walk quietly along the Macuco Trail to spot colorful toucans, curious coatis, and even howler monkeys if you’re lucky. For a more immersive experience, consider joining a guided jungle walk from local naturists.

Day 7: Explore Córdoba

Founded in 1573, Córdoba is home to South America’s oldest university and a collection of Jesuit buildings that form a UNESCO World Heritage Site. Today, with a large student population, Córdoba combines this academic heritage with a contemporary cultural scene, marked by its distinctive cuarteto music and a thriving alternative rock scene.

Things to do in Córdoba

Córdoba blends colonial history with modern student life. The city's Jesuit heritage earned UNESCO status, while its universities ensure a vibrant cultural scene.

Historic Quarter

In the Manzana Jesuítica (Jesuit Block), you’ll find some of Córdoba’s best-preserved colonial architecture. Starting at the National University, you can visit the Jesuit Church, the crypt, and the Jesuit Library, which holds a rare collection of manuscripts. If there’s an exhibition on while you are there, it’s worth a look.

Güemes cultural circuit

Güemes has a distinct creative atmosphere and has become a hub for the city’s art scene. The area’s galleries, many set in renovated factories, showcase local artwork and crafts. The weekend artisan market runs through several blocks, featuring everything from handmade crafts to street food.

Evening in Nueva Córdoba

An evening in Nueva Córdoba is a chance to experience the city’s traditional music and dance. Cuarteto music is often played at peñas, or folk music venues, where locals gather to dance and enjoy regional dishes. Spending time here offers a close look at the region’s music culture. The atmosphere is welcoming.

If you want to spend more time in this fascinating city, consider expanding your trip.

Day 8: Travel from Córdoba to Mendoza

Travel time: 1 hour 15 minutes flight.

Traveling from Córdoba to Mendoza is straightforward, with multiple daily flights taking just 1 hour and 15 minutes. The transfer from Córdoba’s city center to the airport is about a 30-minute drive, and once you land in Mendoza, it’s only 20 minutes by taxi or remis to reach the city center.

Where to stay in Mendoza

Mendoza offers a range of accommodation options:

• City Center: Staying here places you close to restaurants, cafes, and Plaza Independencia, the city’s main square. The streets are lined with large, shade-giving trees.
• Chacras de Coria: About 15 minutes from downtown, this village-like area is surrounded by vineyards, giving it a relaxed, countryside feel. Boutique hotels here offer a quieter alternative with a strong wine country vibe.
• Luján de Cuyo: Known for its wine lodges, this area is a good choice if you want to immerse yourself in vineyard life. Many lodges are part of bodegas (wineries), where you can enjoy views of the Andes at sunset and breakfast among the vines.

Things to do in Mendoza

Mendoza is the heart of Argentina’s wine industry, producing nearly two-thirds of the country’s wine. Framed by the Andes, the city itself is an impressive oasis in the desert, thanks to its historic system of irrigation channels, or acequias. These channels have created lush, tree-lined streets and open plazas that give Mendoza its distinct character.

Plaza circuit

Start at Plaza Independencia, the central square, then visit the four smaller plazas connected by pedestrian streets. If you’re there in the morning, stop by Plaza Italia’s antiques market for unique souvenirs. Plaza España is especially photogenic.

Parque General San Martín

This large park, designed by renowned landscape architect Carlos Thays, is a green escape with fantastic views of the Andes. For panoramic views, climb Cerro de la Gloria within the park, or relax at the rose garden, which features over 500 varieties. The park comes alive in the late afternoon.

Evening food scene

In the evening, head to Aristides Street, where you’ll find a variety of wine bars and restaurants. Take a walk along the pedestrian areas and stop to try local specialties like grilled kid goat or fresh pasta. For dessert, the local ice cream shops offer wine-inspired flavors; the Malbec chocolate flavor is particularly popular.

Day 9: Visit the vineyards

Mendoza’s wine heritage is rich, with roots tracing back to the 16th century when Spanish colonists planted the first vines. Today, Argentina is internationally celebrated for Malbec, a grape that has flourished in the country’s unique terroir.

High altitudes, intense sunlight, and meltwater from the Andes make this region ideal for wine production, establishing Argentina as one of the world’s top wine producers. Here, wine isn’t just a product; it’s woven into everyday life, from family gatherings to the traditional asado (barbecue). Visiting Mendoza’s vineyards offers a close-up look at this deeply rooted culture.

Luján de Cuyo

Known as the birthplace of Argentine Malbec, Luján de Cuyo is filled with family-owned vineyards offering intimate tastings. Start at a historic bodega to see traditional winemaking methods and then visit some of the newer producers to compare. Many wineries here offer multi-course lunches that pair beautifully with limited-edition wines.

Uco Valley

With vineyards reaching up to 1,500 meters, Uco Valley provides stunning views of the Andes and a cooler climate that results in distinct wine profiles. The architectural style of many wineries here is as impressive as their winemaking techniques, showcasing a blend of modern design and innovative approaches. 

Maipú Heritage Route

Maipú, a historic wine region, offers a mix of old-world charm and casual exploration. Some of the wineries here date back to the 1800s and still use original equipment. A bicycle tour is a great way to explore Maipú, as the flat terrain and short distances make it easy for casual cyclists. Many routes also include stops at olive oil producers.

Where to stay near the wineries

For a full wine-country experience, consider staying at a wine lodge in Luján de Cuyo or in the village of Chacras de Coria:

• Luján de Cuyo Wine Lodges: Staying in a wine lodge means you’ll be surrounded by vineyards, with views of misty mountains in the morning and the chance to enjoy private tastings in the evening. Many lodges also offer discounts on wine for their guests, which can make a difference if you’re planning to bring bottles home.
• Chacras de Coria: Just 15 minutes from Mendoza city, Chacras de Coria combines a relaxed wine-country feel with access to city amenities. It’s an excellent choice if you’d like to explore the vineyards but also want dining and shopping options nearby.

Day 10: Back to Buenos Aires or Patagonia

Today, you have two options: return to Buenos Aires for your international connection or continue your journey into Patagonia for more exploration. Both destinations have morning and afternoon flights, though morning departures tend to have fewer delays.

Option 1: Return to Buenos Aires

If you’re heading back to Buenos Aires, the flight from Mendoza to Jorge Newbery Airport (AEP) takes about 1 hour and 40 minutes. As you fly, you’ll have a final glimpse of the Pampas region. Once you land, it’s a 20-minute drive to central neighborhoods like Palermo or Recoleta, making it easy to squeeze in a last dinner in the city.

If you’re connecting to an international flight from Ezeiza (EZE), plan for at least 4 hours between your arrival at AEP and your international departure. The cross-city transfer between the airports can take up to 90 minutes in heavy traffic.

Option 2: Fly to El Calafate, Patagonia

For those continuing to Patagonia, the flight from Mendoza to El Calafate is approximately 3 hours and 30 minutes. This route offers impressive views of the Andes and glacial lakes, so booking a window seat on the left side of the plane is well worth it.

El Calafate’s airport is small but modern. However, it’s a good idea to arrange your transfer to town in advance, as taxis can be limited, especially during peak season.